Peritonitis rates with biocompatible and conventional peritoneal dialysis solutions

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Biocompatible Solutions for Peritoneal Dialysis

In 1978, a simplified technique for peritoneal dialysis (PD) using plastic bags and glucose as osmotic agent allowed PD to become accepted as a home-based renal replacement therapy. However, PD was marred by complications including peritonitis and loss of function of the peritoneal membrane. Both complications may be favored by the bioincompatibility of PD solutions. The composition of PD solut...

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Association of biocompatible peritoneal dialysis solutions with peritonitis risk, treatment, and outcomes.

BACKGROUND AND OBJECTIVES The effect of biocompatible peritoneal dialysis (PD) solutions on PD-related peritonitis is unclear. This study sought to evaluate the relationship between use of biocompatible solutions and the probability of occurrence or clinical outcomes of peritonitis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The study included all incident Australian patients receiving PD ...

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Inflammation and Metabolism in Peritoneal Dialysis – Factors Associated with Peritoneal Function, Peritonitis and Dialysis Solutions

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Conventional versus biocompatible peritoneal dialysis fluids: more questions than answers?

The most important challenge in peritoneal dialysis (PD) is long-term preservation of peritoneal membrane structure and function. Introduction of dialysis fluids into the peritoneal cavity induces changes. These changes are related to duration of dialysis, occurrence of peritonitis and components of the dialysis solution. Bioincompatibility is considered to be the major cause of the development...

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The effects of biocompatible compared with standard peritoneal dialysis solutions on peritonitis microbiology, treatment, and outcomes: the balANZ trial.

BACKGROUND A multicenter, multi-country randomized controlled trial (the balANZ study) recently reported that peritonitis rates significantly improved with the use of neutral-pH peritoneal dialysis (PD) solutions low in glucose degradation products ("biocompatible") compared with standard solutions. The present paper reports a secondary outcome analysis of the balANZ trial with respect to perit...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2012

ISSN: 0085-2538

DOI: 10.1038/ki.2012.46